Imugene is a clinical stage immuno-oncology company developing a range of new treatments that seek to activate the immune system of cancer patients to identify and eradicate tumors.
Azer-cel
UPDATE
Azer-cel (azercabtagene zapreleucel) is an off-the-shelf (allogeneic) cell therapy CAR T drug which targets CD19 to treat blood cancers. It is currently in a Phase 1b trial dosing diffuse large B cell lymphoma (DLBCL) patients who have relapsed off autologous CAR T therapy.
onCARlytics (CF33-CD19) is a novel and effective combination immunotherapy utilising the CF33 oncolytic virus to deliver and present CD19 antigen on the surface of cancer cells promoting CD19 CAR T cell anti-tumour responses against solid tumours.
Our lead candidate is a chimeric vaccinia (pox) virus known as CF33, developed by Professor Yuman Fong, at the prestigious City of Hope Comprehensive Cancer Center in Los Angeles, California.
B-cell immunotherapies are cancer vaccines that vaccinate and induce the body to produce antibodies against validated oncology targets, such as HER2 (HER-Vaxx) or PD-1 (PD1-Vaxx).
Our product pipeline includes multiple immunotherapy B-cell vaccine candidates and an oncolytic virotherapy (CF33) aimed at treating a variety of cancers in combination with standard of care drugs and emerging immunotherapies such as CAR T’s for solid tumours.
Read our latest Health Care: Biotechnology Equity Research and Company Notes.
CEO UPDATE : After yet another busy few months for Imugene in which we’ve taken several pivotal steps forward, I’m thrilled to bring you the latest edition of our shareholder newsletter.
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